CALCIUM CARBONATE (CORAL GRAINS)+ FOLIC ACID+VITAMIN B6+ METHYLECOBALAMIN+VITAMIN D3 SOFTGEL

BRAND NAME-SINUCAL-PLUS SOFTGELS

COMPOSITION: CALCIUM CARBONATE (CORAL GRAINS) 225MG + FOLIC ACID 1.5MG + VITAMIN B6 3.0MG + METHYLCOBALAMIN 1500MCG + VITAMIN D3 200IU SOFT GEL CAPSULES

PACKING : 10*1*10 SOFTGELS BLISTER PACKING

CALCIUM CARBONATE (CORAL GRAINS)

Coral calcium is a supplement usually derived from coral sand deposits. These sand deposits, which were once part of a coral reef, are typically collected directly from coastal land or shallow waters surrounding it.

To manufacture coral calcium, the coral sand deposits are first refined to remove any pollutants or other unwanted substances, then ground into a powder. This powder is sold as-is or packaged into capsules.

Coral calcium supplements are comprised largely of calcium carbonate but may also contain small amounts of magnesium and other trace minerals.

BENEFITS OF CORAL CALCIUM

  • It’s less dense than calcium carbonate from limestone, and absorbs quickly into your bloodstream.
  •  It’s easier for your stomach to handle.
  • It has greater surface area: because of all the holes, one gram of coral calcium is larger than one gram of other types of calcium carbonate. This means that gram for gram, more calcium is exposed to and absorbed by the cells in your body.
  • It has high bioavailability: high absorption means more calcium reaches your system, and less leaves your body as waste. So you get the coral calcium benefits: sango calcium, magnesium and various other coral minerals you need.

FOLIC ACID

Folate (vitamin B9) is an essential nutrient that is required for  DNA replication and as a substrate for a range of enzymatic reactions involved  in amino acid synthesis and vitamin metabolism.

Demands for folate increase during pregnancy because it is also required for  growth and development of the fetus. Folate deficiency has been associated with  abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses
(congenital abnormalities).

Dietary supplementation with folic acid around the time of conception has  long been known to reduce the risk of neural tube defects (NTDs) in the  offspring.

VITAMIN B6(Pyridoxine)

Vitamin B-6 (pyridoxine) is important for normal brain development and for keeping the nervous system and immune system healthy.

Vitamin B6 is needed for the proper function of sugars, fats, and proteins in the body. It’s also necessary for the development of the brain, nerves, skin, and many other parts of the body. It’s found in cereals, legumes, and eggs, and often used with other B vitamins in vitamin B complex products.

METHYLCOBALAMIN

Vitamin B6 and vitamin B12 have significant roles in homocysteine (Hcy)  regulation. In the pathophysiology of PCOS, a positive correlation has been  reported between IR and elevated Hcy levels. Kaya et al. demonstrated that IR,
obesity, and increased Hcy levels were related to low serum insulin B12  concentrations in women with PCOS. In order to reduce elevated levels of serum  Hcy, folic acid supplementation for 3 months produced effective results, especially
in women without insulin resistance.
Metformin inhibits the binding intrinsic factor–B12 complex and its receptor,  and also serum vitamin B12 and folic acid levels
decrease during metformin therapy. Metformin increases Hcy levels. Supplements  of vitamins had no effects on androgen and
lipid levels in the pathophysiology of PCOS. 

VITAMIN D3

Vitamin D3, is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D, CALCIUM, and phosphorus is important for building and keeping strong bones. Vitamin D is used to treat and prevent bone disorders (such as RICKETS, OSTEOMALACIA). Vitamin D is made by the body when Skin is exposed to sunlight. 


Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia 

INDICATIONS OF SINUCAL-PLUS SOFTGELS

1.Senile osteoporosis:

Senile osteoporosis is bone loss that results from aging. It may cause no symptoms at first, but it can lead to fractures and difficulty moving. Senile osteoporosis develops as an adult grows older. It can weaken bones and increase the risk of fractures and other injuries.

2.Drug induced osteoporosis:

Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering. from chronic debilitating diseases. Glucocorticoids are the drugs causing osteoporotic fractures most. frequently, but osteoporosis with fractures is observed also in women treated with aromatase inhibitors for.

3.Post menopauseal osteoporosis:

Postmenopausal osteoporosis is osteoporosis that results from decreased estrogen levels. There are usually no obvious symptoms, and people typically only realize that they have the condition once they have broken a bone. A doctor may use a bone density scan to help diagnose a person with postmenopausal osteoporosis.

Ppostmenopausal osteoporosis generally develops after menopause, when estrogen levels drop precipitously. These changes lead to bone loss, usually in the trabecular (spongy) bone inside the hard cortical bone.

4. Pregnancy and lactation

5.Prevention of osteopenia:

Osteopenia is a loss of bone mineral density (BMD) that weakens bones. It’s more common in people older than 50, especially women. Osteopenia has no signs or symptoms, but a painless screening test can measure bone strength. Certain lifestyle changes can help you preserve bone density and prevent osteoporosis.

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