COMBIKIT:TABLET CLOMIPHENE CITRATE + N-ACETYLECYSTEINE, CAPSULES ASTAXANTHIN

BRAND-NAME: FEOFER-OVA COMBIKIT

COMPOSITION: Each kit having :

EACH TABLET CONTAINS : CLOMIPHENE CITRATE 50MG + N-ACETYLECYSTEINE 600MG

EACH CAPSULES CONTAINS : ASTAXANTHIN 4MG

PACKING-KIT OF 5 TABLETS AND 25 CAPSULES

CLOMIPHENE CITRATE

Clomiphene citrate is the treatment of first choice in the management of infertility in normally oestrogenized, anovulatory women (WHO group II). The majority of women with ‘pure’ anovulatory infertility respond to treatment with clomiphene citrate. 

Among couples unable to conceive without any identifiable cause, 30% are defined as having unexplained infertility. Management depends on duration of infertility and age of female partner. In order to increase pregnancy rate, couples with infertility of unknown origin can undergo ovulation induction and intrauterine insemination. These techniques are able to increase pregnancy rate in case of unexplained infertility. Clomiphene citrate and menopausal or recombinant gonodotropins are the most used drugs to induce ovulation.

MECHANISM

CLOMIPHENE works by making the body think that your estrogen levels are lower than they are, which causes the pituitary gland to increase secretion of follicle stimulating hormone, or FSH, and luteinizing hormone, or LH. Higher levels of FSH stimulate the ovary to produce an egg follicle, or multiple follicles, that will develop and be released during ovulation. High levels of LH stimulate ovulation.

N-ACETYLECYSTEINE (NAC)

NAC is a safe and well-tolerated adjuvant to clomiphene citrate for induction of ovulation can improve the ovulation and pregnancy rates in PCOS patients. It may also have some beneficial impacts on endometrial thickness.

NAC can be an effective adjuvant in PCOS related and unexplained female infertility. The effect could be more profound in women with high BMI, insulin resistance, and oxidative stress

ASTAXANTHIN

Astaxanthin is a red pigment that belongs to a group of chemicals called carotenoids.

Astaxanthin is an antioxidant. This effect might protect cells from damage. Astaxanthin might also improve the way the  immune system functions.

People use astaxanthin for many purposes, including Alzheimer disease , athletic performance, aging skin, muscle soreness from  exercise, and many others.

INDICATIONS OF FEOFER-OVA KIT

For treating female infertility resulting from:

  • Ovulatory dysfunction
  • Poly cystic ovary syndrome (PCOS)
  • Amenorrhea-galactorrhoea syndrome
  • Psychogenic amenorrhea

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