FEROUS BIS GLYCINATE+FOLIC ACID+ZINC BIS GLYCINATE+METHYLCOBALAMIN TABLETS

BRAND NAME: SAPSYL-FE TABLETS

COMPOSITION: FEROUS BIS GLYCINATE 60MG+ FOLIC ACID IP 1MG+ ZINC BIS GLYCINATE 15MG + METHYLCOBALAMIN 500 MCG TABLETS

PACKING: 10*10 TABLETS BLISTER PACK

FEROUS BIS GLYCINATE

Ferrous bisglycinate is a chelate that is used as a source of dietary iron. It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

WHY FERROUS BISGLYCINATE IS BETTER THAN FERROUS SULFATE

  • In the prevention of iron deficiency (ID) and iron deficiency anemia (IDA) in pregnant women. , ferrous bisglycinate was not inferior to ferrous sulfate.
  • The frequency of gastrointestinal complaints was lower in the ferrous bisglycinate than in the ferrous e sulfate group .
  • Newborns weight was slightly higher in the bisglycinate vs. the sulfate group. 
  • Iron from ferrous bisglycinate is better absorbed than is iron from ferrous sulfate. 

FOLIC ACID

Folate (vitamin B9) is an essential nutrient that is required for DNA replication and as a substrate for a range of enzymatic reactions involved in amino acid synthesis and vitamin metabolism.

Demands for folate increase during pregnancy because it is also required for growth and development of the fetus. Folate deficiency has been associated with abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses (congenital abnormalities).

Dietary supplementation with folic acid around the time of conception has long been known to reduce the risk of neural tube defects (NTDs) in the offspring.

ZINC BIS GLYCINATE

Poor maternal zinc status has been associated with foetal loss, congenital malformations, intrauterine growth retardation, reduced birth weight, prolonged labour and preterm or post-term deliveries.

Zinc plays an important role in many biological functions including protein synthesis, cellular division and nucleic acid metabolism

METHYLCOBALAMIN (vitamin B-12)

Pregnant women in resource-poor areas are at risk of multiple micronutrient deficiencies, and diets that are low in animal products place women at increased risk of vitamin B-12 deficiency .

Vitamin B-12 acts as a cofactor in the conversion of homocysteine to methionine, as well as the formation of succinyl-CoA from l-methylmalonyl-CoA. Deficiency of vitamin B-12 causes macrocytic anemia, neurologic dysfunction, and biochemical abnormalities related to the accumulation of the precursor moieties (hyperhomocysteinemia and methylmalonic acidemia).

In turn, hyperhomocysteinemia has been linked to a higher risk of multiple adverse outcomes of pregnancy, including delivering an infant small for gestational age or with intrauterine growth retardation (IUGR), low birth weight (LBW), pregnancy-induced hypertension, neural tube defects, and preterm delivery.

maternal supplementation during pregnancy and early lactation with 50 μg of daily oral vitamin B-12 significantly improved maternal plasma and breast milk measures of vitamin B-12 status, as well as multiple measures of infant vitamin B-12 status.

INDICATIONS OF SAPSYL-FE TABLETS

1.Iron Deficiency Anaemia:

Iron deficiency anemia is a common type of anemia — a condition in which blood lacks adequate healthy red blood cells. Red blood cells carry oxygen to the body’s tissues.

Symptoms:

Initially, iron deficiency anemia can be so mild that it goes unnoticed. But as the body becomes more deficient in iron and anemia worsens, the signs and symptoms intensify.

Iron deficiency anemia signs and symptoms may include:

  • Extreme fatigue
  • Weakness
  • Pale skin
  • Chest pain, fast heartbeat or shortness of breath
  • Headache, dizziness or lightheadedness
  • Cold hands and feet
  • Inflammation or soreness of your tongue
  • Brittle nails
  • Unusual cravings for non-nutritive substances, such as ice, dirt or starch
  • Poor appetite, especially in infants and children with iron deficiency anemia

2. Megaloblastic Anaemia:

Megaloblastic anemia is characterized by RBCs that are larger than normal. There also aren’t enough of them.

When RBCs aren’t produced properly, it results in megaloblastic anemia. Because the blood cells are too large, they may not be able to exit the bone marrow to enter the bloodstream and deliver oxygen.

3.Acute/Chronic blood loss.

4.Pregnancy.

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